Abstract:It is a Cu-Pb-Zn-Ag polymetallic ore with several valuable elements in the ore, but the disseminated grain size of valuable minerals is fine, heterogeneous and complex. It is extraordinary unusual in domestic that the study of process mineralogy showed that the main copper mineral was tetrahedrite and most of silver also occurred in it in the form of isomorphism. Selective flotation process was adopted to treat the ores with MT-20 and BITCM as copper and lead collector respectively. Finally the concentrates of copper and lead grading 18.18% Cu and 55.56% Pb were obtained, at recoveries of 81.03% Cu and 72.63% Pb respectively. It is proved that the process is easily to be operated, the flotation indexes are stable and the recovery of valuable minerals is high, as well as the purpose of comprehensive recycle is achieved.