Abstract:A lead-zinc ore with zinc of 2.25%, and lead of 1.96%, contains associated silver with grade at 13.20 g/t. The lead and zinc in the ore are mainly exist in the form of galena and sphalerite which are closely associated and complex disseminated with each other. In order to realize the high efficient exploitation and utilization of the resources, beneficiation tests of the ore were made. Results obtained by differential flotation showed that, when the grinding fineness was 65.00% passing 74 μm, adopting lime as pulp pH regulator, zinc sulfate as depressor, diethyldithiocarbamate as collector, via the process of lead concentration by one roughing, two scavenging and regrinding the lead rough concentrate with fineness at 82.70% passing 37 μm, then followed by two cleaning; for the tailing of lead flotation, adopting lime as pulp pH regulator, copper sulphate as activator, butyl xanthate as collector, via the flowsheet of zinc concentration by one roughing, two scavenging and two cleaning. Finally, results showed that the lead concentrate with lead grade of 66.43% and lead recovery of 95.97%, silver grade of 309.71g/t and silver recovery of 74.87%, and zinc concentrate with zinc grade of 53.35%, zinc recovery of 90.35%．