Abstract:The effect of the addition order of inorganic regulators (zinc sulfate, copper sulfate, sodium sulfite and sodium sulfide) on the flotation of typical sulfide minerals (chalcopyrite, galena, sphalerite and pyrite) was investigated using diethyldithiocarbamate as collector. Results of flotation tests show that it has different effects of the adding order exchange of regulators and collector on the variation rules of the flotation recovery of the sulfide minerals. As compared to the inorganic regulators added first, when the diethyldithiocarbamate is added first, the depression effects of zinc sulfate on the flotation of chalcopyrite and galena weaken; the depression effects of zinc sulfate, low dosage of copper sulfate, sodium sulfite and sodium sulfide on the flotation of sphalerite and that of copper sulfate on the flotation of chalcopyrite and galena enhance; the activation effects of zinc sulfate and copper sulfate on the flotation of pyrite and that of high dosage of copper sulfate on the flotation of sphalerite are equivalent; it has little effect of sodium sulfite and sodium sulfide on the flotation of chalcopyrite, galena and pyrite. The research results can provide reference for part of sulfide minerals improving the efficiency of mineral flotation separation by exchanging the adding order of the regulators and collector.