Abstract:The gold grade of a gold ore is 1.96g/t, and the gold mainly occurs in the natural gold, with a high content of coarse-grained gold. The organic carbon content in the ore reaches 1.39%, and the total content of clay minerals such as chlorite, muscovite, and kaolinite is relatively high. The ore is a refractory gold ore with high content of carbon and slime. Based on the ore properties and the dissemination characteristics of the gold minerals, a combined beneficiation and metallurgical process was used to recover gold from the ore ,consisting of “Knelson gravity separation of raw ore - flotation of gravity tailings - leaching of flotation concentrate”. The results showed that using carboxymethyl cellulose (CMC) as gangue minerals depressant, compared to sodium silicate, can shorten the flotation process, significantly enhance the grade of the flotation gold concentrate, and decrease reagent usage. By using the carbon-in-leach (CIL) process, activated carbon can compete with organic carbon in the ores to adsorb gold, which is beneficial for eliminating the “gold robbery” phenomenon due to high organic carbon content. With this combined process, the gold recovery rate can achieve 90.93%, which can provide technical reference for the similar ores.