Abstract:A complex refractory copper-zinc ore has low copper-zinc grade ratio, many kinds of zinc minerals, and great floatability difference, moreover, copper and zinc minerals are complexly associated and wrapped with each other, and some chalcopyrite is fine in particle size and distributed in sphalerite in solid solution separation structure. Based on detailed analysis of ore properties and on-site process investigation, the experimental study adopts the mineral processing technology of “copper zinc equal flotation + copper zinc separation after regrinding + enhanced zinc flotation + combined cleaning of copper-zinc separation tailings and enhanced zinc coarse concentrate” and the new copper-zinc separation inhibitor ZJ407,which obtained copper concentrate with copper grade of 14.45% and copper recovery rate of 46.03% and zinc concentrate with zinc grade of 45.52% and zinc recovery rate of 88.27%. Compared with the on-site "copper-zinc preferential flotation" process, the obtained concentrates have low mutual metal content and high recovery rate of main metal. The experimental conclusion provides a basis for the technical transformation of the on-site production of this ore and a technical reference for the recovery of the same kind of ore.